The Utrecht Metabolism Expertise Center (MEC) specialises in cellular metabolomics and lipidomics. We use state-of-the-art mass spectrometry to identify and quantify small-molecule metabolites and lipids in biological systems. These metabolites are part of a complex network of biochemical reactions and are highly affected by genetic or environmental changes (e.g. disease, drug treatment). At MEC, it is our mission to translate metabolite measurements into meaningful insights into the biological system at hand.
MEC’s expertise is in targeted and untargeted metabolomics, lipidomics and fluxomics. Fluxomics experiments use stable-isotope labeled substrates and allow for measuring pathway activities, thereby providing a highly dynamic understanding of cellular metabolism.
MEC offers full metabolomics and lipidomics support, from experimental design to data interpretation. Our service involves the high-quality measurements of metabolites in different sample types (e.g. cells, tissues, body fluids). With our extensive experience, we also provide advice on experimental setup, perform data analysis and visualisation and support with data interpretation.
The unique and large-scale open facility Exposome-Scan gives researchers from all over the Netherlands the opportunity to study the exposome. Anyone who submits a good research request will have access to the research facility and will be able to conduct research at Exposome-Scan at cost price. The facility in Leiden opens on 15 February 2024 and builds on the knowledge gained in the Exposome-NL and X-omics research programmes.
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