Amy Harms

Amy Harms manages the Metabolomics Core Facility at Leiden University, embedded in the Analytical Biosciences division of the LACDR. She received her PhD in chemistry from Penn State in 1994 and did post-doctoral research in the field of biological mass spectrometry at Pacific Northwest National Lab.  After working as a mass spectrometry facility manager in the University of Kentucky, she moved to Wisconsin and in 1998 became the director of the Mass Spectrometry/ proteomics/ metabolomics facility at the University of Wisconsin Biotechnology Center and ran the core facility for the University of Wisconsin Comprehensive Cancer Center until moving to the Netherlands.

Amy’s interests include instrumentation, data processing strategies, and quality control.  As research support, she hopes to contribute to the experimental design, the actual collecting of data, evaluation and interpretation of data, and integration of metabolomics into the larger goals of the proposed projects.

Publications

Reconstruction of Glutathione Metabolism in the Neuronal Model of Rotenone-Induced Neurodegeneration Using Mass Isotopologue Analysis...

Luojiao Huang, Nicolas Drouin, Jason Causon, Agnieszka Wegrzyn, Jose Castro-Perez, Ronan Fleming, Amy Harms, Thomas Hankemeier
Analytical Chemistry (volume 95, issue 6)

Severe COVID-19 Is Characterised by Perturbations in Plasma Amines Correlated with Immune Response Markers, and Linked to Inflammation and Oxidative Stress

Naama Karu, Alida Kindt, Adriaan J van Gammeren, Anton A M Ermens, Amy C Harms, Lutzen Portengen, Roel C H Vermeulen, Willem A Dik, Anton W Langerak, Vincent H J van der Velden, Thomas Hankemeier
Metabolites (volume 12, issue 7)

Plasma Oxylipins and Their Precursors Are Strongly Associated with COVID-19 Severity and with Immune Response Markers

Naama Karu, Alida Kindt, Lieke Lamont, Adriaan J van Gammeren, Anton A M Ermens, Amy C Harms, Lutzen Portengen, Roel C H Vermeulen, Willem A Dik, Anton W Langerak, Vincent H J van der Velden, Thomas Hankemeier
Metabolites (volume 12, issue 7)

Amy Harms

Contact information

a.c.harms@lacdr.leidenuniv.nl

 

 

Decoding the exposome

Decoding the exposome

The environment we live in has a dominant impact on our health. It explains an estimated seventy percent of the chronic disease burden. Where we live, what we eat, how much we exercise, the air we breathe and whom we associate with; all of these environmental factors play a role. The combination of these factors over the life course is called the exposome. There is general (scientific) consensus that understanding more about the exposome will help explain the current burden of disease and that it provides entry points for prevention and ...

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