The development of portable, unobtrusive sensing devices and, where possible, their integration with smartphones, which most people already carry, opens the door for continuous and widespread sensing systems. In this project we will build on previous experience of using and developing sensors and Apps in exposome research. Initially, these new tools will be implemented in the reference Exposome panel study to test their validity and ease of use. Exposome tools with proven utility will subsequently be applied to longitudinal cohorts (across the Netherlands) with intense phenotyping and biological samples to enable the linkage between external and internal Exposome measures and health
We know far less about the exposome than we do about the human genome. So far, we only understand about half of the disease burden for which we know the environment plays a role. If we want to prevent people from becoming ill, then we need to understand the other half too. We therefore want to systematically analyse the exposome for the first time. We will start with research into the causes of cardiovascular disease and type 2 diabetes. The techniques and insights from this research will also be applicable to other chronic conditions.
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