The characterisation of the exposome and of its health consequences defines a complex research framework, which requires the development of novel analytical strategies combining statistical, data science, and bioinformatic approaches. The cross-cutting theme on statistical developments will develop and implement new statistical tools that will be used in Exposome-NL. These tools will be made available via Bioconductor both internally and externally to Exposome-NL, and yearly training workshops will be organized to disseminate knowledge throughout Exposome-NL. During the course of Exposome-NL new data challenges will arise and the project will adapt its research in later years based on identified unified data-problems within Exposome-NL.
The environment we live in has a dominant impact on our health. It explains an estimated seventy percent of the chronic disease burden. Where we live, what we eat, how much we exercise, the air we breathe and whom we associate with; all of these environmental factors play a role. The combination of these factors over the life course is called the exposome. There is general (scientific) consensus that understanding more about the exposome will help explain the current burden of disease and that it provides entry points for prevention and ...
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