X.2 Ethics by design

In this project, we will identify and evaluate the ethical challenges raised by the Exposome-NL Project. We will use an interdisciplinary approach that will deploy empirical and normative methods as well as Public and Patient Involvement (PPI) elements

Publications

Nature-versus-nurture considered harmful: Actionability as an alternative tool for understanding the exposome from an ethical perspective

Caspar W. Safarlou, Roel Vermeulen, Karin R. Jongsma
Bioethics (2024)

Enabling the Nonhypothesis-Driven Approach: On Data Minimalization, Bias, and the Integration of Data Science in Medical Research and Practice

C. W. Safarlou, M. van Smeden, R. Vermeulen, K. R. Jongsma
The American Journal of Bioethics Volume 23, 2023 - Issue 9

The Ethical Aspects of Exposome Research: A Systematic Review

Caspar W Safarlou, Karin R Jongsma, Roel Vermeulen, Annelien L Bredenoord
Exposome

Scrutinizing Privacy in Multi-Omics Research: How to Provide Ethical Grounding for the Identification of Privacy-Relevant Data Properties.

Safarlou CW, Bredenoord AL, Vermeulen R, Jongsma KR.
Am J Bioeth. 2021 Dec;21(12):73-75.

Decoding the exposome

Decoding the exposome

The environment we live in has a dominant impact on our health. It explains an estimated seventy percent of the chronic disease burden. Where we live, what we eat, how much we exercise, the air we breathe and whom we associate with; all of these environmental factors play a role. The combination of these factors over the life course is called the exposome. There is general (scientific) consensus that understanding more about the exposome will help explain the current burden of disease and that it provides entry points for prevention and ...

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