Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study

Marwah Doestzada, Daria V. Zhernakova, Inge C. L. van den Munckhof, Daoming Wang, Alexander Kurilshikov, Lianmin Chen,Vincent W. Bloks, Martijn van Faassen, Joost H. W. Rutten, Leo A. B. Joosten, Mihai G. Netea, Cisca Wijmenga, Niels P. Riksen, Alexandra Zhernakova, Folkert Kuipers, and Jingyuan Fu
BMC Medicine, vol. 20 issue 1

Influence of the microbiome, diet and genetics on inter-individual variation in the human plasma metabolome

Lianmin Chen, Daria V Zhernakova, Alexander Kurilshikov, Sergio Andreu-Sánchez, Daoming Wang, Hannah E Augustijn, Arnau Vich Vila; Lifelines Cohort Study; Rinse K Weersma, Marnix H Medema, Mihai G Netea, Folkert Kuipers, Cisca Wijmenga, Alexandra Zhernakova, Jingyuan Fu
Nature medicine, vol. 28 issue 11

gutSMASH predicts specialized primary metabolic pathways from the human gut microbiota

Victòria Pascal Andreu, Hannah E Augustijn, Lianmin Chen, Alexandra Zhernakova, Jingyuan Fu, Michael A Fischbach, Dylan Dodd, Marnix H Medema
Nature biotechnology (Feb 2023)

Reconstruction of Glutathione Metabolism in the Neuronal Model of Rotenone-Induced Neurodegeneration Using Mass Isotopologue Analysis...

Luojiao Huang, Nicolas Drouin, Jason Causon, Agnieszka Wegrzyn, Jose Castro-Perez, Ronan Fleming, Amy Harms, Thomas Hankemeier
Analytical Chemistry (volume 95, issue 6)

Severe COVID-19 Is Characterised by Perturbations in Plasma Amines Correlated with Immune Response Markers, and Linked to Inflammation and Oxidative Stress

Naama Karu, Alida Kindt, Adriaan J van Gammeren, Anton A M Ermens, Amy C Harms, Lutzen Portengen, Roel C H Vermeulen, Willem A Dik, Anton W Langerak, Vincent H J van der Velden, Thomas Hankemeier
Metabolites (volume 12, issue 7)

Decoding the exposome

The environment we live in has a dominant impact on our health. It explains an estimated seventy percent of the chronic disease burden. Where we live, what we eat, how much we exercise, the air we breathe and whom we associate with; all of these environmental factors play a role. The combination of these factors over the life course is called the exposome. There is general (scientific) consensus that understanding more about the exposome will help explain the current burden of disease and that it provides entry points for prevention and ...

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