Metabolomics

Publications

mzQuality: An Open-Source Software Tool for Quality Monitoring and Reporting of Targeted Mass Spectrometry Measurements

van der Peet M, Maas P, Wegrzyn A, Lamont L, Fleming R, Bordes C, Debette S, Harms A, Hankemeier T, Kindt A.
J Am Soc Mass Spectrom (2025)

Strategies for Using Postcolumn Infusion of Standards to Correct for Matrix Effect in LC-MS-Based Quantitative Metabolomics

Anne-Charlotte Dubbelman, Bo van Wieringen, Lesley Roman Arias, Michael van Vliet, Roel Vermeulen, Amy C. Harms, and Thomas Hankemeier
Journal of the American Society for Mass Spectrometry (2024)

A comprehensive UHPLC-MS/MS method for metabolomics profiling of signaling lipids: Markers of oxidative stress, immunity and inflammation

Wei Yang, Johannes C. Schoeman, Xinyu Di, Lieke Lamont, Amy C. Harms, Thomas Hankemeier
Analytica Chimica Acta (2024)

Development of targeted hydrophilic interaction liquid chromatography-tandem mass spectrometry method for acyl-Coenzyme A covering short- to long-chain species in a single analytical run

Madhulika Singh, Ligia Akemi Kiyuna, Christoff Odendaal, Barbara M. Bakker, Amy C. Harms, Thomas Hankemeier,
Journal of Chromatography A (2024)

Blood microsampling technologies: Innovations and applications in 2022

Thangavelu MU, Wouters B, Kindt A, Reiss IKM, Hankemeier T.
Analytical Science Advances (2023)

Reconstruction of Glutathione Metabolism in the Neuronal Model of Rotenone-Induced Neurodegeneration Using Mass Isotopologue Analysis ....

Luojiao Huang, Nicolas Drouin, Jason Causon, Agnieszka Wegrzyn, Jose Castro-Perez, Ronan Fleming, Amy Harms, Thomas Hankemeier
Analytical Chemistry (2023)

Severe COVID-19 Is Characterised by Perturbations in Plasma Amines Correlated with Immune Response Markers, and Linked to Inflammation and Oxidative Stress

Naama Karu, Alida Kindt, Adriaan J van Gammeren, Anton A M Ermens, Amy C Harms, Lutzen Portengen, Roel C H Vermeulen, Willem A Dik, Anton W Langerak, Vincent H J van der Velden, Thomas Hankemeier
Metabolites (2022)

Plasma Oxylipins and Their Precursors Are Strongly Associated with COVID-19 Severity and with Immune Response Markers

Naama Karu, Alida Kindt, Lieke Lamont, Adriaan J van Gammeren, Anton A M Ermens, Amy C Harms, Lutzen Portengen, Roel C H Vermeulen, Willem A Dik, Anton W Langerak, Vincent H J van der Velden, Thomas Hankemeier
Metabolites (2022)

Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project

Lopera-Maya EA, Kurilshikov A, van der Graaf A, Hu S, Andreu-Sánchez S, Chen L, Vila AV, Gacesa R, Sinha T, Collij V, Klaassen MAY, Bolte LA, Gois MFB, Neerincx PBT, Swertz MA; LifeLines Cohort Study; Harmsen HJM, Wijmenga C, Fu J, Weersma RK, Zhernakova A, Sanna S.
Nature Genetics (2022)

Decoding the exposome

Decoding the exposome

The environment we live in has a dominant impact on our health. It explains an estimated seventy percent of the chronic disease burden. Where we live, what we eat, how much we exercise, the air we breathe and whom we associate with; all of these environmental factors play a role. The combination of these factors over the life course is called the exposome. There is general (scientific) consensus that understanding more about the exposome will help explain the current burden of disease and that it provides entry points for prevention and ...

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