Clinical Epidemiology

Publications

Association between gut microbiome profiles and host metabolic health across the life course: a population-based study

Li R, Kurilshikov A, Yang S, van Oortmerssen JAE, van Hilten A, Ahmadizar F, Roshchupkin G, Kraaij R, Duijts L, Fu J, Ikram MK, Jaddoe VWV, Uitterlinden AG, Rivadeneira F, Kavousi M, Zhernakova A, Medina-Gomez C.
Lancet Reg Health Eur (2024)

Rome III Criteria Capture Higher Irritable Bowel Syndrome SNP-Heritability and Highlight a Novel Genetic Link With Cardiovascular Traits

Camargo Tavares L, Lopera-Maya EA, Bonfiglio F, Zheng T, Sinha T, Zanchetta Marques F, Zhernakova A, Sanna S, D'Amato M.
Cell Mol Gastroenterol Hepatol (2024)

The Gut Microbiome Composition Is Altered in Long-standing Type 1 Diabetes and Associates With Glycemic Control and Disease-Related Complications

van Heck JIP, Gacesa R, Stienstra R, Fu J, Zhernakova A, Harmsen HJM, Weersma RK, Joosten LAB, Tack CJ.
Diabetes Care (2022)

An association between chronic widespread pain and the gut microbiome

Freidin MB, Stalteri MA, Wells PM, Lachance G, Baleanu AF, Bowyer RCE, Kurilshikov A, Zhernakova A, Steves CJ, Williams FMK.
Rheumatology (Oxford) (2021)

Patient attitudes towards faecal sampling for gut microbiome studies and clinical care reveal positive engagement and room for improvement

Bolte LA, Klaassen MAY, Collij V, Vich Vila A, Fu J, van der Meulen TA, de Haan JJ, Versteegen GJ, Dotinga A, Zhernakova A, Wijmenga C, Weersma RK, Imhann F.
PLoS One (2021)

The Composition and Metabolic Potential of the Human Small Intestinal Microbiota Within the Context of Inflammatory Bowel Disease

Ruigrok RAAA, Collij V, Sureda P, Klaassen MAY, Bolte LA, Jansen BH, Voskuil MD, Fu J, Wijmenga C, Zhernakova A, Weersma RK, Vich Vila A.
J Crohns Colitis (2021)

Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort

Mc Intyre K, Lanting P, Deelen P, Wiersma HH, Vonk JM, Ori APS, Jankipersadsing SA, Warmerdam R, van Blokland I, Boulogne F, Dijkema MXL, Herkert JC, Claringbould A, Bakker O, Lopera Maya EA, Bültmann U, Zhernakova A, Reijneveld SA, Zijlstra E, Swertz MA, Brouwer S, van Ooijen R, Angelini V, Dekker LH, Sijtsma A, Scherjon SA, Wijmenga C, Dekens JAM, Mierau J, Boezen HM, Franke L.
BMJ Open (2021)

Healthy Cotwins Share Gut Microbiome Signatures With Their Inflammatory Bowel Disease Twins and Unrelated Patients

Brand EC, Klaassen MAY, Gacesa R, Vich Vila A, Ghosh H, de Zoete MR, Boomsma DI, Hoentjen F, Horjus Talabur Horje CS, van de Meeberg PC, Willemsen G, Fu J, Wijmenga C, van Wijk F, Zhernakova A, Oldenburg B, Weersma RK; Dutch TWIN-IBD consortium and the Dutch Initiative on Crohn and Colitis.
Gastroenterology (2021)

Decoding the exposome

Decoding the exposome

The environment we live in has a dominant impact on our health. It explains an estimated seventy percent of the chronic disease burden. Where we live, what we eat, how much we exercise, the air we breathe and whom we associate with; all of these environmental factors play a role. The combination of these factors over the life course is called the exposome. There is general (scientific) consensus that understanding more about the exposome will help explain the current burden of disease and that it provides entry points for prevention and ...

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