Services

We have three offerings:

1. MS assays
2. In-vitro assays
3. Data services

Mass-spectrometric exposomics assays

We are offering state-of-the art assays to study the exposome in plasma/serum and other sample types. We are developing our assays further, and plan to launch in the future also new assays (see under development). Below you see our current assays that we offer now or will be able to offer in 2024.

Assays Coverage
Global untargeted
(RPLC-qTOFMS & HILIC-qTOFMS)
Polar and medium polar metabolites covering carbon/energy metabolism, protein metabolism, gut metabolites, polar lipids, di/tri-peptides, exposure markers such as food, drugs, pollutants, and more (>2500 small molecules)
GC-MS GC-Orbitrap for untargeted analysis of semi-volatile environmental chemicals including pesticides, flame retardants, PCBs.
Lipidomics (HILIC-MS/MS) Medium and apolar lipids; >1500 lipids covering >27 lipid classes
Signaling & bioactive lipids
(RPLC-MS/MS)
Oxyplins, isoprostanes, eicosanoids etc informing about inflammation and immune response (>300 bioactive lipids)
Biogenic amines
(RPLC-MS/MS)
Biogenic amines after derivatization incl. polyamines, amino acids, vascular stress markers, tryptophane pathway (>80 biogenic amines)
Other targeted metabolomics platforms CoA esters, acylcarnitines, bile acids
Tracer-based metabolomics
(HILIC-qTOFMS/MS)
> 200 metabolites using Zeno MS/MS to determine mass isotopologue distribution (MID) of intact metabolites and fragmented substructures

In-vitro assays

We will generate metabolites  in lysosomes to allow enzymes to transform targets/suspects. 

Data services

Support for statistical analysis.

Feature ID, annotation, classification, suspect screening.

The full service data analysis will work on all data provided, not just the minimal meta data in our fair data point.

Contact us

Please contact us for more details and if you are interested in our capabilities and services.

You can contact us for:

  • Research questions: expert assistance to help design your own Exposome research project.
  • Outsourcing questions: analyses of samples in one of the facilities.
  • Technical questions: assistance with sample preparation and protocols.

We are committed to FAIR; we are working to make our data as FAIR and methods as FAIR as possible.